Solid-Phase Organic Synthesis

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  • 9780471318255
  • 16 december 1999
  • 296 pagina's
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'Solid-Phase Organic Synthesis' is edited by Kevin Burgess. Efficient, high-throughput chemistry is now the focus of many research laboratories. Solid-phase organic syntheses are central to many of these combinatorial and parallel screening methodologies.

Solid-Phase Organic Synthesis Edited by Kevin Burgess, Texas A & M University Efficient, high-throughput chemistry is now the focus of many research laboratories. Solid-phase organic syntheses are central to many of these combinatorial and parallel screening methodologies. Consequently, they have been a major scientific theme of the 1990s and promise to remain prominent for the first part of the new millennium. Indeed, a bewildering number of papers have entered the literature on this topic; some report minor modifications enabling transformation of solution-phase methods to a solid support, while others report major innovations. Solid-Phase Organic Synthesis collects, highlights, and critiques some of the key developments in the field. Leading practitioners explain different perspectives on diverse aspects of the area. Specific topics covered include:
* Syntheses of guanidines
* Palladium-catalyzed C-C bond forming reactions
* S_nAr reactions for the formation of heterocycles
* Sequence-specific arylalkyne oligomers
* Resin-supported capture agents and other reagents
* Synthesis on pins
* Monitoring of supported reactions using IR
* Solid-phase syntheses of natural product derivatives
Of related interest ... Combinatorial Chemistry and Molecular Diversity in Drug Discovery Eric M. Gordon and James F. Kerwin 1998 (0-471-15518-7) 544 pp. Combinatorial Chemistry Synthesis and Application Stephen R. Wilson and Anthony W. Czarnik 1997 (0-471-12687-X) 288 pp.

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Oorspronkelijke releasedatum
16 december 1999
Aantal pagina's
296

Betrokkenen

Hoofdauteur
K Burgess
Tweede Auteur
Burgess
Hoofdredacteur
K. Burgess
Hoofduitgeverij
Wiley-Interscience

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161 mm
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27 mm
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240 mm
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152 mm
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32 mm
Verpakking lengte
229 mm
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590 g

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9780471318255

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