Inflammation in the Pathogenesis of Chronic Diseases The COX-2 Controversy

Discusses the role of inflammation in the pathogenesis of major chronic diseases and the controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors. This book documents important findings in cancer research showing that selective COX-2 inhibitors have powerful antineoplastic effects against major forms of cancer.



In this book, a worldwide panel of leading experts discuss the role of inflammation in the pathogenesis of major chronic diseases and the current controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors. The authors provide exciting and enlightening perspectives on COX-2 and related molecular targets in the future of medicine, including historical perspectives.