The purpose of this publication is to provide commanders, staffs, key agencies, and Service members with a key reference for understanding, characterizing, and managing CBRN threats and hazards in a particular operational environment (OE). This manual bridges the gap between Service and joint doctrine. It contains TTP for commanders and staff to use for characterizing and managing CBRN threats and hazards while conducting multi-Service military operations. This manual addresses concepts, principles, fundamentals, planning, operational considerations, and training and support functions. It serves as the foundation for developing Service manuals and refining existing training support packages, mission training plans, training center and unit exercises, and Service school curricula. It drives the examination of organizations and materiel developments applicable to military support of CBRN aspects of command and control (C2).