Glioma Immunotherapeutic Approaches

Taal: Engels
Glioma
  • Engels
  • Hardcover
  • 9781461431459
  • Druk: 2012 ed.
  • april 2012
  • 232 pagina's
Alle productspecificaties

Samenvatting

Treatment of glioma is currently one of the most challenging problems in oncology, as well as in neurosurgery. Despite major advances in our understanding of the pathomechanism, diagnosis by imaging and the availability of powerful therapeutic tools, the life expectancy of patients with glioblastoma has only been slightly prolonged and a cure remains elusive. None of the currently available surgical tools, including operative microscopes, lasers and image-guided surgery, can enable the detection and removal of all of the tumor tissue. In recent years, however, the landscape has been changing immeasurably, and molecular studies over the past two decades have identified a variety of genetic aberrations that are specifically associated with individual types of gliomas. In addition, certain molecular abnormalities have been linked to therapy responses, thereby establishing clinical biomarkers and molecular targets, and the use of novel agents is being investigated. These agents have been specifically engineered to exert specific cytotoxicity against gliomas, either on their own as single agents or in combination with other modalities. Moreover, there has been an enormous surge of interest in the area of immunology and immunotherapy, which has been facilitated by our understanding of the molecular basis of gliomas. Although several kinds of immunotherapeutic trials have been undertaken, we still await a great breakthrough in terms of clinical efficacy to prolong the survival time of glioma patients.

Recensie(s)

From the reviews: This textbook is geared mostly toward the immune cell, and cytokine mediated treatment of gliomas in human patients. ... I recommend this book enthusiastically to neurosurgeons and neurooncologists. (Joseph J. Grenier, Amazon.com, June, 2014)

Productspecificaties

Inhoud

Taal
Engels
Bindwijze
Hardcover
Druk
2012 ed.
Verschijningsdatum
2012-04-26
Aantal pagina's
232 pagina's
Illustraties
Nee

Betrokkenen

Redacteur
Ryuya Yamanaka
Uitgever
Springer-Verlag New York Inc.

EAN

EAN
9781461431459

Overige kenmerken

Extra groot lettertype
Nee
NUR code
870
Oorspronkelijke releasedatum
2012-04-26
Subtitel
Immunotherapeutic Approaches
Thema Subject Code
MBGR

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