Terug Terug

Synergistic Interaction & Cell Responses to Environmental Factors

Name: Synergistic Interaction & Cell Responses to Environmental Factors
Author: Vladislav G Petin

Auteur: Vladislav G Petin

Taal: Engels

Afbeeldingen

Artikel vergelijken

Vergelijk met andere artikelen

Bekijk nu

Auteur: Vladislav G Petin J K Kim

Co-auteur: J. K. Kim Vladislav G. Petin Vladislav G Petin J K Kim

Engels
Hardcover
9781631170843
01 mei 2014
320 pagina's

Alle productspecificaties

Samenvatting

For a quantitative description of variety cell responses to ionising radiation, a mathematical model is suggested. In contrast to the conventional point of view that the relative biological effectiveness (RBE) of densely ionising radiation is determined only by physical characteristics of radiation, this book presents extensive experimental data demonstrating the importance of cell recovery ability in the RBE manifestation. The most impressive data obtained was mostly for diploid mutant cells at the log-stage of growth, in which the RBE was close to unity. It was also shown that the recovery process itself was not damaged after exposure to high-LET radiation, as well as the enhanced RBE values due to the increased yield of irreversible radiation damage from which cells were incapable of recovering. A novel direction in the study of radio-protecting and radio-sensitising action of chemical compounds is also discussed and confirmed in the book. A new conception for the mechanism of synergy is suggested, in accordance with the synergy due to the formation of additional effective damages resulting from the interaction of sublesions. These sublesions are supposed to be non-effective when each agent is applied separately. This concept led to the development of original mathematical models of synergy, which is reviewed by the authors. The model predicts a number of general rules of interaction, the condition under which the highest synergy can be achieved, its value, and the dependence of synergy on the intensity of agents applied. Validation of the model was also verified for various physical and chemical factors, biological objects and end points. The theory appears to be appropriate and the conclusions valid.

Productspecificaties

Inhoud

Taal: en
Bindwijze: Hardcover
Oorspronkelijke releasedatum: 01 mei 2014
Aantal pagina's: 320
Illustraties: Nee

Betrokkenen

Hoofdauteur: Vladislav G Petin
Tweede Auteur: J K Kim
Co Auteur: J K Kim
Hoofduitgeverij: Nova Science Publishers

Overige kenmerken

Extra groot lettertype: Nee
Product breedte: 180 mm
Product lengte: 260 mm
Studieboek: Nee
Verpakking breedte: 180 mm
Verpakking hoogte: 260 mm
Verpakking lengte: 260 mm
Verpakkingsgewicht: 782 g

EAN

EAN: 9781631170843

Je vindt dit artikel in

Categorieën: Wetenschap & Natuur

Biologie

Boeken
Taal: Engels
Studieboek of algemeen: Algemene boeken
Boek, ebook of luisterboek?: Boek
Beschikbaarheid: Leverbaar

Reviews

Nog geen reviews

Hoe controleren en plaatsen wij reviews? Hoe controleren en plaatsen wij reviews?

Negatief, positief, neutraal: we zetten een review altijd online. We controleren wel eerst of ’ie voldoet aan onze reviewvoorwaarden en niet nep is. We controleren ook of ’ie is geschreven door iemand die het artikel heeft gekocht via bol.com en zetten dit er dan bij. De controles gebeuren automatisch, al kijken er soms mensen mee. Bol.com betaalt niet voor reviews. Als een reviewer door een andere partij is vergoed, staat dit in de review zelf.