Free Energy Calculations Theory and Applications in Chemistry and Biology

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  • Engels
  • Hardcover
  • 9783540384472
  • 08 januari 2007
  • 536 pagina's
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Samenvatting

Free energy constitutes the most important thermodynamic quantity to understand how chemical species recognize each other, associate or react.



Free energy constitutes the most important thermodynamic quantity to understand how chemical species recognize each other, associate or react. Examples of problems in which knowledge of the underlying free energy behaviour is required, include conformational equilibria and molecular association, partitioning between immiscible liquids, receptor-drug interaction, protein-protein and protein-DNA association, and protein stability.

This volume sets out to present a coherent and comprehensive account of the concepts that underlie different approaches devised for the determination of free energies. The reader will gain the necessary insight into the theoretical and computational foundations of the subject and will be presented with relevant applications from molecular-level modelling and simulations of chemical and biological systems. Both formally accurate and approximate methods are covered using both classical and quantum mechanical descriptions. A central theme of the book is that the wide variety of free energy calculation techniques available today can be understood as different implementations of a few basic principles.

The book is aimed at a broad readership of graduate students and researchers having a background in chemistry, physics, engineering and physical biology.

Productspecificaties

Inhoud

Taal
en
Bindwijze
Hardcover
Oorspronkelijke releasedatum
08 januari 2007
Aantal pagina's
536
Illustraties
Nee

Betrokkenen

Hoofdredacteur
Christophe Chipot
Tweede Redacteur
Andrew Pohorille
Co Redacteur
C. Chipot
Hoofduitgeverij
Springer

Overige kenmerken

Editie
2007 ed.
Extra groot lettertype
Nee
Product breedte
155 mm
Product hoogte
38 mm
Product lengte
235 mm
Studieboek
Nee
Verpakking breedte
162 mm
Verpakking hoogte
35 mm
Verpakking lengte
238 mm
Verpakkingsgewicht
1056 g

EAN

EAN
9783540384472
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Bindwijze : Hardcover

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