Introduction to Statistical Genetic Data

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  • Engels
  • Paperback
  • 9780262538381
  • 18 februari 2020
  • 432 pagina's
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Samenvatting

A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics. Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required. The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.

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Inhoud

Taal
en
Bindwijze
Paperback
Oorspronkelijke releasedatum
18 februari 2020
Aantal pagina's
432
Illustraties
Nee

Betrokkenen

Hoofdauteur
Melinda C. Mills
Tweede Auteur
Nicola Barban
Co Auteur
Felix C. Tropf
Hoofduitgeverij
Mit Press

Overige kenmerken

Extra groot lettertype
Nee
Product breedte
178 mm
Product hoogte
25 mm
Product lengte
229 mm
Studieboek
Ja
Verpakking breedte
172 mm
Verpakking hoogte
30 mm
Verpakking lengte
227 mm
Verpakkingsgewicht
975 g

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EAN
9780262538381
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