"The Royal Society of Chemistry (RSC) is a learned society (professional association) in the United Kingdom with the goal of ""advancing the chemical sciences"". It was formed in 1980 from the amalgamation of the Chemical Society, the Royal Institute of Chemistry, the Faraday Society, and the Society for Analytical Chemistry with a new Royal Charter and the dual role of learned society and professional body. At its inception, the Society had a combined membership of 34,000 in the UK and a further 8,000 abroad. The headquarters of the Society are at Burlington House, Piccadilly, London. It also has offices in Thomas Graham House in Cambridge (named after Thomas Graham, the first president of the Chemical Society) where RSC Publishing is based. The Society has offices in the United States at the University City Science Center, Philadelphia, in both Beijing and Shanghai, China and Bangalore, India. The organisation carries out research, publishes journals, books and databases, as well as hosting conferences, seminars and workshops. It is the professional body for chemistry in the UK, with the ability to award the status of Chartered Chemist (CChem) and, through the Science Council the awards of Chartered Scientist (CSci), Registered Scientist (RSci) and Registered Science Technician (RScTech) to suitably qualified candidates. The designation FRSC is given to a group of elected Fellows of the society who have made major contributions to chemistry and other interface disciplines such as biological chemistry. The names of Fellows are published each year in The Times (London). Honorary Fellowship of the Society (""HonFRSC"") is awarded for distinguished service in the field of chemistry.
This book presents the papers and recorded discussion of the 161st Faraday Discussion. Organised by the Royal Society of Chemistry, this event took place in London in September 2012.
One of the key challenges in biophysics and chemical biology is gaining an understanding of the underlying physico-chemical basis of the highly complex structure and properties of biomembranes. It used to be thought that the lipid component played a mainly passive role, simply acting as a self-assembled bilayer matrix within which the active protein components functioned. However, it has now become clear that there is a intimate two-way interplay between the lipid and the protein components in determining membrane structure, organization and dynamics, and that lipids play many active roles in biological function. Concepts such as lateral segregation and domain formation, lateral pressure, curvature and curvature elasticity have attracted enormous interest in recent years, although their validity when applied to real biomembranes remains unclear or even obscure.
This Faraday Discussion considered recent developments in the study of biomembrane structure, ordering and dynamics, with particular emphasis on the roles of lipids in these phenomena. As well as discussing new experimental and theoretical findings and novel methodologies, the meeting focused on exploring the relevance of concepts from amphiphile self-assembly and soft matter physics to understanding biomembranes.
One of the key challenges in biophysics and chemical biology is gaining an understanding of the underlying physico-chemical basis of the highly complex structure and properties of biomembranes. It used to be thought that the lipid component played a mainly passive role, simply acting as a self-assembled bilayer matrix within which the active protein components functioned. However, it has now become clear that there is a intimate two-way interplay between the lipid and the protein components in determining membrane structure, organization and dynamics, and that lipids play many active roles in biological function. Concepts such as lateral segregation and domain formation, lateral pressure, curvature and curvature elasticity have attracted enormous interest in recent years, although their validity when applied to real biomembranes remains unclear or even obscure. This Faraday Discussion considered recent developments in the study of biomembrane structure, ordering and dynamics, with particular emphasis on the roles of lipids in these phenomena. As well as discussing new experimental and theoretical findings and novel methodologies, the meeting focused on exploring the relevance of concepts from amphiphile self-assembly and soft matter physics to understanding biomembranes.
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