The Art of Process Chemistry
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Auteur:
N Yasuda
- Engels
- Hardcover
- 9783527324705
- 27 oktober 2010
- 298 pagina's
Samenvatting
Providing vital knowledge for the pharmaceutical industry and process chemists, this ready reference presents successful strategies for the hottest drug candidates, showing how to manufacture valuable products in an economical, sustainable and robust way.
The refinement of a chemical process to the point where it becomes both cost and time efficient can be seen as "art." In a competitive environment where pharmaceutical companies are under ever increasing pressure to bring new drugs more quickly to the market, ways need to be found to provide bulk supplies of drug candidates as quickly as possible and to design manufacturing routes, which are robust, economical and environmentally firendly. This monograph is divided into 9 chapters, each one concentrating on a single class of drug candidates of chemistry development and describing the routes explored and the optimizations made to each drug candidate, inluding the discovery of applicable new chemistry and the elucidation of reaction mechanism.
The refinement of a chemical process to the point where it becomes both cost and time efficient can be seen as "art." In a competitive environment where pharmaceutical companies are under ever increasing pressure to bring new drugs more quickly to the market, ways need to be found to provide bulk supplies of drug candidates as quickly as possible and to design manufacturing routes, which are robust, economical and environmentally firendly. This monograph is divided into 9 chapters, each one concentrating on a single class of drug candidates of chemistry development and describing the routes explored and the optimizations made to each drug candidate, inluding the discovery of applicable new chemistry and the elucidation of reaction mechanism.
From the contents:
- Efairenz®, a Non-Nucleoside Reverse Transciptase Inhibitor (NNRTI), and a Previous Structurally Related Development Candidate
- CCR5 Receptor Antagonist
- 5α-Reductase Inhibitors – The Finsteride Story
- Rizatriptan (Maxalt®): A 5-HT1D Receptor Agonist
- SERM: Selective Estrogen Receptor Modulator
- HIV Integrase Inhibitor: Raltegravir
- Cyclopentane-Based NK1 Receptor Antagonist
- Glucokinase Activator
- CB1R Inverse Agonist – Taranabant
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Inhoud
- Taal
- en
- Bindwijze
- Hardcover
- Oorspronkelijke releasedatum
- 27 oktober 2010
- Aantal pagina's
- 298
- Illustraties
- Nee
Betrokkenen
- Hoofdauteur
- N Yasuda
- Hoofdredacteur
- Nobuyoshi Yasuda
- Hoofduitgeverij
- Wiley Vch
Overige kenmerken
- Extra groot lettertype
- Nee
- Product breedte
- 175 mm
- Product hoogte
- 18 mm
- Product lengte
- 246 mm
- Studieboek
- Nee
- Verpakking breedte
- 178 mm
- Verpakking hoogte
- 21 mm
- Verpakking lengte
- 244 mm
- Verpakkingsgewicht
- 690 g
EAN
- EAN
- 9783527324705
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