Developmental Toxicology

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  • Engels
  • Paperback
  • 9781138372443
  • 14 november 2018
  • 408 pagina's
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Samenvatting

Highlighting latest advances in genetics and biochemistry, the completely revised Third Edition reviews the field from basic science, clinical, epidemiological, and regulatory perspectives. Contributions from top opinion leaders in the field bring together developments in molecular embryology and cell biology as they apply to problems in developmental toxicology. It covers testing of pharmaceutical and environmental agents and interpretation of developmental toxicology data, highlighting mathematical and statistical techniques, as well as the effects of toxic exposure on the functional development of various organs. The relationship between maternal and developmental toxicology is examined, in addition to current techniques for studying chemical disposition, metabolism, and placental transfer. Close attention is given to the regulatory aspects of testing and risk assessment. Pre- and postconceptional clinical care and genetic factors in clinical developmental toxicology are also discussed. Key topics include: the roles of apoptosis and signal transduction pathways in normal and abnormal development the role of epigenetic changes in development the role of nutrition and individual susceptibility the utility of bioinformatics global and targeted gene expression changes

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Inhoud

Taal
en
Bindwijze
Paperback
Oorspronkelijke releasedatum
14 november 2018
Aantal pagina's
408
Illustraties
Nee

Betrokkenen

Hoofdauteur
Deborah K. Hansen
Tweede Auteur
Barbara D. Abbott
Co Auteur
Barbara D. Abbott
Hoofduitgeverij
Crc Press

Overige kenmerken

Editie
3
Extra groot lettertype
Nee
Product breedte
152 mm
Product lengte
229 mm
Studieboek
Nee
Verpakking breedte
152 mm
Verpakking hoogte
229 mm
Verpakking lengte
229 mm
Verpakkingsgewicht
453 g

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EAN
9781138372443
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