Mass Spectrometry of Nucleosides and Nucleic Acids

Afbeeldingen

Artikel vergelijken

  • Engels
  • Paperback
  • 9780367384685
  • 23 september 2019
  • 504 pagina's
Alle productspecificaties

Samenvatting

Assembling the work of an international panel of researchers, Mass Spectrometry of Nucleosides and Nucleic Acids summarizes and reviews the latest developments in the field and provides a window on the next generation of analysis. Beginning with an overview of recent developments, the book highlights the most popular ionization methods and illustrates the diversity of strategies employed in the characterization and sequencing of DNA and RNA oligomers, nucleosides, nucleotides, and adducts. It describes studies performed on deoxyinosine and its analogues and provides an introduction to tandem mass spectrometry (MS/MS).

Next, the contributors examine mass spectrometric application in the study of cyclic nucleotides in biochemical signal transduction. They analyze urinary modified nucleosides and explore DNA adducts. They discuss isotope labeling of DNA-mass spectrometry (ILD-MS) and examine various uses of electrospray ionization mass spectrometry (ESI-MS). The book reviews recent progress in the direct MS characterization of noncovalent nucleic acid-protein complexes, explores the interaction and ionization of guanidine-derived compounds with highly acidic biomolecules, and examines quantitative identification of nucleic acids via signature digestion products detected using mass spectrometry.

The book describes a direct-infusion ESI-MS approach that can serve as a screening technique for the presence of modified nucleosides from small RNAs. Lastly, it discusses the LC-MS/MS method for the in vitro replication studies on damage-containing DNA substrates, and concludes with an examination of the influence of metal ions on the structure and reactivity of nucleic acids.

The exciting developments in mass spectrometry technology have fueled incredible advances in our understanding of nucleic acids and their complexes. The contributions presented in this volume capture the range of these advances, helping to inspire new findings a

Productspecificaties

Inhoud

Taal
en
Bindwijze
Paperback
Oorspronkelijke releasedatum
23 september 2019
Aantal pagina's
504
Illustraties
Nee

Betrokkenen

Hoofdredacteur
Joseph H. Banoub
Tweede Redacteur
Patrick A. Limbach
Hoofduitgeverij
Crc Press

Overige kenmerken

Extra groot lettertype
Nee
Product breedte
178 mm
Product lengte
254 mm
Studieboek
Nee
Verpakking breedte
178 mm
Verpakking hoogte
254 mm
Verpakking lengte
254 mm
Verpakkingsgewicht
929 g

EAN

EAN
9780367384685

Je vindt dit artikel in

Taal
Engels
Boek, ebook of luisterboek?
Boek
Beschikbaarheid
Leverbaar
Studieboek of algemeen
Studieboeken
Nog geen reviews

Kies gewenste uitvoering

Bindwijze : Paperback

Prijsinformatie en bestellen

De prijs van dit product is 72 euro en 56 cent.
2 - 3 weken
Verkoop door bol
In winkelwagen
  • Prijs inclusief verzendkosten, verstuurd door bol
  • Ophalen bij een bol afhaalpunt mogelijk
  • 30 dagen bedenktijd en gratis retourneren
  • Dag en nacht klantenservice

Lijst met gekozen artikelen om te vergelijken

Vergelijk artikelen