Oxidative Injury and Dopaminergic Neurodegeneration Role of oxidative stress in pathogenesis of Parkinson's Disease

Afbeeldingen

Artikel vergelijken

  • Engels
  • Paperback
  • 9783659226762
  • 31 augustus 2012
  • 100 pagina's
Alle productspecificaties

Samenvatting

The major anatomical features of Parkinson's disease (PD) are the decrease in the number of neuromelanin-containing neurons located in the midbrain substantia nigra compacta (SNC). These dopaminergic neurons are projected to the striatum as well as a number of other subcortical regions. Degradation of the dopaminergic neurons located in the SNC and a subsequent loss of dopaminergic nerve terminals in the striatum are responsible for most of the movement disorders. Although the underlying cause of dopaminergic cell death or process by which these cells degenerate in PD is not clearly understood but oxidative stress is thought to play an important role. Oxidative stress is characterized by decreased levels of glutathione and impaired mitochondrial complex I. Besides the decreased levels of glutathione and impaired mitochondrial complex I, another important component supporting the role of oxidative stress in PD is heavy metals like Iron, Aluminum and Mercury.

Productspecificaties

Inhoud

Taal
en
Bindwijze
Paperback
Oorspronkelijke releasedatum
31 augustus 2012
Aantal pagina's
100
Illustraties
Nee

Betrokkenen

Hoofdauteur
Aryal Bijay

Overige kenmerken

Extra groot lettertype
Nee
Product breedte
152 mm
Product hoogte
6 mm
Product lengte
229 mm
Studieboek
Nee
Verpakking breedte
152 mm
Verpakking hoogte
6 mm
Verpakking lengte
229 mm
Verpakkingsgewicht
159 g

EAN

EAN
9783659226762

Je vindt dit artikel in

Nog geen reviews

Kies gewenste uitvoering

Bindwijze : Paperback

Prijsinformatie en bestellen

De prijs van dit product is 46 euro en 99 cent.
3 - 4 weken
Verkoop door bol
  • Prijs inclusief verzendkosten, verstuurd door bol
  • Ophalen bij een bol afhaalpunt mogelijk
  • 30 dagen bedenktijd en gratis retourneren
  • Dag en nacht klantenservice