Protein Quality Control in Neurodegenerative Diseases
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- Engels
- Hardcover
- 9783642279270
- 12 december 2012
- 135 pagina's
Samenvatting
Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding., translocation, and clearance of proteins. The cell is challenged constantyl by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding., translocation, and clearance of proteins. The cell is challenged constantyl by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
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- Bindwijze
- Hardcover
- Oorspronkelijke releasedatum
- 12 december 2012
- Aantal pagina's
- 135
- Illustraties
- Nee
Betrokkenen
- Hoofdredacteur
- Richard I. Morimoto
- Tweede Redacteur
- Yves Christen
- Hoofduitgeverij
- Springer-Verlag Berlin and Heidelberg GmbH & Co. K
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- 2013 ed.
- Extra groot lettertype
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- Product breedte
- 155 mm
- Product lengte
- 235 mm
- Studieboek
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- 159 mm
- Verpakking hoogte
- 15 mm
- Verpakking lengte
- 241 mm
- Verpakkingsgewicht
- 358 g
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- EAN
- 9783642279270
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