A Simple Guide To Genetic Diseases, Diagnosis, Treatment And Related Conditions Ebook Tooltip Ebooks kunnen worden gelezen op uw computer en op daarvoor geschikte e-readers.
Afbeeldingen
Sla de afbeeldingen overArtikel vergelijken
- Engels
- E-book
- 9780463209530
- 20 oktober 2019
- Epub zonder kopieerbeveiliging (DRM)
Samenvatting
This book describes Genetic Diseases, Diagnosis and Treatment and Related Diseases
A genetic disease is a disease produced by an abnormality in the genetic makeup of an individual called a variation or a change of a gene called a mutation.
The genetic abnormality can vary from minor to major from a single mutation in a single base in the DNA of a single gene to a large chromosomal abnormality involving the addition or subtraction of a complete chromosome or set of chromosomes.
Some people become heir to genetic disorders from the parents, while acquired changes or mutations in a pre-existing gene or group of genes produce other genetic diseases.
Genetic mutations can happen either randomly or due to some environmental exposure.
There are 4 different types of genetic disorders (inherited), such as:
A. Single gene inheritance
Single gene inheritance is also termed Mendelian or monogenetic inheritance.
Alterations or mutations that happen in the DNA sequence of a single gene produce this type of inheritance.
Monogenetic disorders are relatively infrequent and are produced by a mutation in a single gene.
The mutation may be evident on one or both chromosomes (one chromosome inherited from each parent).
Some monogenic disorders are:
- Sickle cell disease,
- Cystic fibrosis,
- Polycystic kidney disease
- Marfan syndrome,
- Fragile X syndrome,
- Huntington's disease,
- Hemochromatosis
- Alpha and beta-thalassemias,
- Tay-Sachs disease.
A mutated gene can be passed on through a family.
B. Multi-factorial genetic inheritance
Multi-factorial inheritance is also termed complex or polygenic inheritance.
Multi-factorial inheritance disorders are caused by a combination of environmental factors and mutations in multiple genes.
Most genetic disorders are multi-factorial inheritance disorders, meaning they are caused by a combination of inherited mutations in multiple genes, often working together with environmental factors.
Some frequent chronic diseases are multi-factorial disorders. - Heart disease,
- High blood pressure,
- Alzheimer's disease,
- Arthritis
- Diabetes
- Cancer and
- Obesity
C. Chromosomal abnormalities
Since chromosomes are the carriers of the genetic material, abnormalities in chromosome number or structure can cause disease.
Chromosomal abnormalities normally occur as a result of a problem with cell division.
Chromosomes injury is in the changes in the number or structure of complete chromosomes, the structures that carry genes
Chromosome disorders are produced by an excess or deficiency of the genes that are sited on chromosomes, or by structural alterations within chromosomes.
A specific type of blood cancer (chronic myeloid leukemia) may be produced by a chromosomal translocation, in which parts of 2 chromosomes (chromosomes 9 and 22) are exchanged.
Down’s syndrome or trisomy 21 is a frequent genetic disorder that occurs when a person has 3 copies of chromosome 21 even though no individual gene on the chromosome is abnormal.
There are many other chromosomal abnormalities: - Turner syndrome (45, X0),
- Klinefelter syndrome (47, XXY)
D. Mitochondrial genetic inheritance
This form of genetic disorder is caused by mutations in the non-nuclear DNA of mitochondria.
Mitochondrial DNA is always inherited from the female parent
Nearly all diseases have a genetic constituent.
Updates in genetic diseases involve a better knowledge of the DNA or microRNA.
TABLE OF CONTENT
Introduction
Chapter 1 Genetic Diseases
Chapter 2 Down’s Syndrome
Chapter 3 Marfan’s Syndrome
Chapter 4 Turner’s Syndrome
Chapter 5 Klinefelter’s Syndrome
Chapter 6 Hemophilia
Chapter 7 Lynch Syndrome
Chapter 8 G6PD Deficiency
Chapter 9 Huntington’s Chorea
Chapter 10 Sickle Cell Anemia
Chapter 11 Thalassemia
Chapter 12 Hemochromatosis
Chapter 13 Cystic Fibrosis
Chapter 14 Polycystic Kidneys
Chapter 15 Muscle Dystrophy
Chapter 16 Fragile X Syndrome
Epilogue
Productspecificaties
Inhoud
- Taal
- en
- Bindwijze
- E-book
- Oorspronkelijke releasedatum
- 20 oktober 2019
- Ebook Formaat
- Epub zonder kopieerbeveiliging (DRM)
Betrokkenen
- Hoofdauteur
- Kenneth Kee
- Hoofduitgeverij
- Smashwords Edition
Lees mogelijkheden
- Lees dit ebook op
- Android (smartphone en tablet) | Kobo e-reader | Desktop (Mac en Windows) | iOS (smartphone en tablet) | Windows (smartphone en tablet)
Overige kenmerken
- Studieboek
- Nee
EAN
- EAN
- 9780463209530
Je vindt dit artikel in
- Categorieën
- Taal
- Engels
- Boek, ebook of luisterboek?
- Ebook
- Beschikbaar in Kobo Plus
- Beschikbaar in Kobo Plus
- Beschikbaarheid
- Leverbaar
Kies gewenste uitvoering
Prijsinformatie en bestellen
De prijs van dit product is 2 euro en 68 cent.- E-book is direct beschikbaar na aankoop
- E-books lezen is voordelig
- Dag en nacht klantenservice
- Veilig betalen
Rapporteer dit artikel
Je wilt melding doen van illegale inhoud over dit artikel:
- Ik wil melding doen als klant
- Ik wil melding doen als autoriteit of trusted flagger
- Ik wil melding doen als partner
- Ik wil melding doen als merkhouder
Geen klant, autoriteit, trusted flagger, merkhouder of partner? Gebruik dan onderstaande link om melding te doen.