Drug Discovery Series- Handbook of Assay Development in Drug Discovery

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  • Engels
  • Hardcover
  • 9781574444711
  • 20 januari 2006
  • 488 pagina's
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Samenvatting

Describes the tools available for performing various assay techniques. This book presents descriptions of methods, laboratory guidelines and protocols used to perform such methods, specific examples of each assay system and troubleshooting tools. It describes biochemical assay classes and non-class specific assay development for cell-based assays.



The need to screen targets faster and more efficiently, coupled with advances in parallel and multiplex chemical synthesis, has contributed to the increasing use of multiwell assays for drug discovery. The Handbook of Assay Development in Drug Discovery is a reference that describes the complete armament of tools currently available for performing various assay techniques.

Featuring contributions from assay developers in the pharmaceutical and vendor communities, the book presents descriptions of methods, laboratory guidelines and protocols used to perform such methods, specific examples of each assay system, and troubleshooting tools. The handbook describes biochemical assay classes as well as non-class specific assay development for cell-based assays. It covers a wide range of target classes—including kinases, proteases, nuclear receptors, and GPCRs—and describes currently employed methods and assay types, such as radioligand binding assays, image analysis assays, enzyme fragment complementation, and bioluminescent and fluorescent-based assays.

Designed as a guide to running an assay from start to finish, the Handbook of Assay Development in Drug Discovery is an ideal bench top companion for discovery researchers, laboratory managers, academics, and other scientists involved in drug discovery screening, lead profiling, therapeutic target evaluation, and assay development and implementation in the pharmaceutical and biotechnology industries.

Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.

Productspecificaties

Inhoud

Taal
en
Bindwijze
Hardcover
Oorspronkelijke releasedatum
20 januari 2006
Aantal pagina's
488
Illustraties
Nee

Betrokkenen

Hoofdauteur
Lisa Minor
Tweede Auteur
Lisa Minor K Minor
Hoofdredacteur
Lisa K. Minor
Hoofduitgeverij
CRC Press Inc

Vertaling

Originele titel
Handbook of Assay Development in Drug Discovery

Overige kenmerken

Editie
illustrated edition
Extra groot lettertype
Nee
Product breedte
178 mm
Product lengte
254 mm
Studieboek
Nee
Verpakking breedte
178 mm
Verpakking hoogte
254 mm
Verpakking lengte
254 mm
Verpakkingsgewicht
1020 g

EAN

EAN
9781574444711

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